This Peptide Burns Fat and Builds Muscle — But the Man Who Discovered It Won't Take It - Yet

GLP-1 family of drugs are a remarkable advance in human health. However, there are some major downsides of GLP-1. The biggest one is muscle loss. Up to 30% of the weight people lose on GLP-1 is muscle. MOTC, by the way, maintain muscle mass in various models, but also prevents osteoporosis in various mass models. They lost weight, they improved their blood sugar,

helps with fat loss, helps build, if not at least prevent the loss of lean tissue, and helps metabolic health, mitochondrial function. Sounds too good to be true, right?

That's the beauty of the 503A path, that it will allow people to have access to potentially valuable products, peptides, that aren't proven to be really effective. They may be, but they're at least considered safe. A lot of money has gone in to develop interventions for Alzheimer's disease. tens of billions of dollars with really nothing that works we discovered one such peptide that we call schmooze 20 of europeans have a mutation in schmooze that makes it less active and they have a 50 increase in the risk of alzheimer's

disease do you think there is ever a world where we replace some of these major lifestyle interventions with a peptide

so i'm a big believer

Hassi, I am so excited to have you here today for a whole host of reasons. Peptides is the thing that everyone is talking about right now. There is so much confusion, so much misinformation. And I think despite everyone having an opinion on it, there's probably not that many people who are qualified to do so. And so I think that a really good place to start would be why you are so qualified to do so you know i know you spent your career studying um these mitochondrial derived peptides specifically and then maybe give us like a really high level definition of what they are and i think we hear differing opinions here too a nice easy one to start

First of all, Chris, it's great to be here, and I really think this is a very important vision to communicate. I'm an endocrinologist by training, and my entire career has been focused on hormones and how they can be used to improve human health. And before the concept of peptides became a thing, many of the hormones that we worked with were in fact peptides. The best example is insulin, which is a peptide that has profound effects on blood sugar and metabolism. And my career transitioned from working on the standard hormones like insulin and growth hormone, which was my area of expertise, in the 20th century to work specifically on peptides. Because in the turn of the century, I was working on an obscure molecule known as IGF-BP3, which was a regulator of IGF-1, which is also a peptide. And in fact, there are forms of IGF-1 that are among the different peptides people tend to use these days.

IGF being insulin growth factor.

Insulin-like growth factor. And we were intrigued by the fact that this IGF-BP3 molecule seemed to have done all sorts of things beyond binding the insulin-like growth factor, IGF. so we used a technique called yeast to hybrid system which is a very complicated genetic screen for protein protein interaction and we cloned a new molecule that later became known as humanin which the intriguing part about it it