Legal Opinion
Dana-Farber Cancer Inst., Inc. v. Ono Pharm. Co.
District Court, District of Columbia
Decided May 17, 2019No. Civil Action No. 15-13443-PBSPublishedCited by 5 opinions
1Opinion of the Court
Hon. Patti B. Saris, Chief United States District Judge
TABLE OF CONTENTS
INTRODUCTION...60
FINDINGS OF FACT...60
I. Scientific Background...60
A. The Immune System and Receptor-Ligand Signaling...60
B. Experimental Methods...63
II. Discoveries of PD-1 and 292...64
A. Dr. Honjo Discovers the PD-1 Receptor...64
B. Dr. Honjo Asks for Help Identifying the Ligand for PD-1 and Begins to Collaborate with Dr. Wood in September 1998...65
C. Dr. Freeman Discovers the 292 Ligand in July 1998...65
D. Dr. Wood Connects the PD-1/PD-L1 Pathway in September 1999...68
III. October 25, 1999 Collaboration Meeting in…
2Cases cited55 opinions
- A.C. Aukerman Company v. R.L. Chaides Construction Co.Court of Appeals for the Federal Circuit · 1992
- Colorado v. New MexicoSupreme Court of the United States · 1984
- Richard C. Price v. Dale R. SymsekCourt of Appeals for the Federal Circuit · 1993
- Pfizer, Inc. v. Apotex, Inc.Court of Appeals for the Federal Circuit · 2007
- Ethicon, Inc. And Inbae Yoon, M.D. v. United States Surgical Corporation and Young Jae ChoiCourt of Appeals for the Federal Circuit · 1998
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3Cited by5 opinions
- Dana-Farber Cancer Institute v. Ono Pharmaceutical Co., Ltd.Court of Appeals for the Federal Circuit · 2020
- Dana-Farber Cancer Institute, Inc. v. Bristol-Myers Squibb Co.District Court, D. Massachusetts · 2021
- Dana-Farber Cancer Institute, Inc. v. Bristol-Myers Squibb Co.District Court, D. Massachusetts · 2021
- Nexus Technologies, Inc. v. Unlimited Power Ltd.District Court, W.D. North Carolina · 2020
- Nordstrom Consulting, Inc.; Steven Nordstrom v. Innova Systems, Inc.; Cheryl Nordstrom, individuallyDistrict Court, N.D. Illinois · 2026