Publication

Management of Severe Pediatric Lower Lip Defect After Canine Bite with Polyhexamethylene Biguanide (PHMB), Full-Thickness Skin Graft (FTSG) and Compression Foam: A Case Report

Sep 28, 2025 · 7 authors · 22 topics

Abstract

Introduction: Pediatric lower-lip dog bite injuries are challenging due to contamination, tissue loss, and the need to maintain function, appearance, and psychological well-being. This single case describes immediate definitive closure using sharp debridement with adjunct polyhexanide (PHMB), a full-thickness skin graft (FTSG), and a polyurethane (PU) compression foam bolster. Methods: A 10-year-old boy with a severe contaminated lower-lip defect underwent debridement and 0.04% PHMB irrigation. An upper-arm FTSG was inset and compressed with a suture-anchored PU dressing. Topical PHMB gel was used perioperatively and for seven days after bolster removal. Oral antibiotics were given for five days. The patient was discharged eight days after the injury with detailed wound care instructions. Results: Immediate definitive closure was achieved with complete graft survival and no infection, necrosis, unplanned early dressing changes, or reoperations. At 12 months, oral competence, speech, lip mobility, and contour were preserved. However, mild residual esthetic differences remained (dyschromia, shallow border indentation, vellus hairs on the graft). Conclusion: In this single descriptive case, primary closure of a lower lip injury with the combined intervention was associated with an uncomplicated functional Children 2025, 12, 1308 https://doi.org/10.3390/children12101308 Children 2025, 12, 1308 2 of 12 course and manageable esthetic trade-offs at 12 months. These observations are descriptive; comparative studies with standardized functional, esthetic, and psychosocial measures are needed. Keywords: pediatric; lip; dog; bite; polyhexamethylene biguanide; polyhexanide; PHMB; graft; FTSG

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Authors

Aba LőrinczHermann NudelmanAnna Gabriella LambertiAttila M. VastyanEmese Paari‐MolnarGábor PavlovicsGergő Józsa

Topics

Rabies epidemiology and controlVirus-based gene therapy researchVirology and Viral DiseasesCase ReportAba L˝orincz 1,2 , Hermann Nudelman 1,2 , Anna Gabriella Lamberti 1,2 , Attila Vástyán 1, Enik˝o Molnár 1,Gábor Pavlovics 3 and Gerg˝o Józsa 1,2,*1 Division of Pediatric Surgery, Traumatology, Urology and Pediatric Otolaryngology, Department of Pediatrics,Clinical Complex, University of Pécs, 7 József Attila Street, 7623 Pécs, Hungary; aba.lorincz@gmail.com (A.L.);nuhwaao.pte@tr.pte.hu (H.N.); lamberti.anna@pte.hu (A.G.L.); vastyan.attila@pte.hu (A.V.);molnar.eniko@pte.hu (E.M.)2 Department of Thermophysiology, Institute for Translational Medicine, Medical School, University of Pécs,12 Szigeti Street, 7624 Pécs, Hungary3 Plastic and Burn Surgery Department, Surgical Clinic, Clinical Complex, University of Pécs, Ifjúság Street 13,7624 Pécs, Hungary; pavlovics.gabor@pte.huCorrespondence: jozsa.gergo@pte.hu; Tel.: +36-30-514-2730HighlightsWhat are the main findings?• Primary closure was achieved in a large, lower-lip defect after a dog bite using an integrated approach (topical polyhexanide, FTSG secured with a polyurethane com pression foam, oral antibiotics).• Function remained intact; at 12 months, modest esthetic sequelae persisted (dyschro mia, shallow border indentation, vellus hairs).• This pediatric case shows that the combined intervention can yield stable function with moderate esthetic compromise in a contaminated, extensive lower-lip injury.• Component-level effects are undetermined; comparative studies with validated out comes are needed.What are the implications of the main findings?

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PublishedSep 28, 2025
TypeArticle
Citations0
References39

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