Double‐Dummy

Abstract

Abstract Blinding embodies a rich history spanning several centuries. Double‐blinding usually reduces differential assessment of outcomes (information bias), but can also improve compliance and retention of trial participants while reducing biased supplemental care or treatment (sometimes called co‐intervention). With an active treatment control group, different options to double‐blinding present production obstacles, compliance impediments, and unblinding opportunities. To double‐blind in this situation, double‐dummy blinding nearly always becomes indispensable.

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