Publication

Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT

Mar 1, 2020 · 14 authors · 3 topics

Abstract

Reports are published in Health Technology Assessment (HTA) if (1) they have resulted from work for the HTA programme, and (2) they are of a sufficiently high scientific quality as Patients were eligible to participate in the trial if they had hydrocephalus of any aetiology (including idiopathic intracranial hypertension) requiring a first ventriculoperitoneal shunt. Note that failed primary endoscopic third ventriculostomy, indwelling ventricular access device (e.g. Ommaya or Rickham reservoir or ventriculosubgaleal shunt or similar) and indwelling external ventricular drains were allowed. Patients with the following characteristics were excluded from the trial: l previous indwelling ventricular or lumbar peritoneal or atrial shunt l active and ongoing cerebrospinal fluid or peritoneal infection (previous infected cases were allowed once cleared of infection) l multiloculated hydrocephalus requiring multiple ventriculoperitoneal shunts or neuroendoscopy l ventriculoatrial or ventriculopleural shunt planned l allergy to antibiotics associated with the antibiotic shunt l allergy to silver.

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Authors

8 of 14
Conor L. MallucciMichael D. JenkinsonElizabeth J. ConroyJohn C. HartleyMichaela BrownTracy MoittJoanne DaltonTom Kearns

Topics

Cerebrospinal fluid and hydrocephalusHead and Neck Surgical OncologySpinal Dysraphism and Malformations

About

PublishedMar 1, 2020
TypeArticle
Citations24
References54

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