Process for preparing chiral sulphoxides (US Patent 5068369)

Patent number: 5068369 Granted: 1991-11-26 Filed: 1990-09-28 Inventors: Stephen G. Davies (Oxford, GB2) Assignees: The British Petroleum Company p.l.c. (London, GB2)

Abstract

A process for preparing single enantiomers of chiral sulphoxides is provided. The process involves (a) reacting an achiral sulphur-containing compound, e.g. a disulphide, with a single enantiomer of a chiral template having the formula T-(CO)-CH.sub.2 R.sup.1, wherein T is suitably (eta.sup.5 -C.sub.5 H.sub.5)Fe(CO)(PPh.sub.3)- (Ph=phenyl) and (b)