Non-steroidal polycyclic ring sulphamate derivatives, their preparation and their use as oestrone sulphatase inhibitors (US Patent 6239169)

Patent number: 6239169 Granted: 2001-05-29 Filed: 1998-08-14 Inventors: Michael J. Reed (London, GB); Barry V. Potter (Bath, GB) Assignees: Sterix Limited (Oxford, GB)

Abstract

A non-steroidal compound suitable for use as an inhibitor of oestrone sulphatase. The compound has a polycyclic ring structure comprising two or more rings wherein at least two of the rings mimic the A and B rings of oestrone. The compound can have the general formula A