Chimeric DNA polymerases (US Patent 9388396)

Patent number: 9388396 Kind code: B2 Granted: 2016-07-12 Filed: 2014-05-05 Inventors: Bjarne Faurholm (Western Cape, ZA); Paul McEwan (Western Cape, ZA); William Bourn (Western Cape, ZA); Gavin Rush (Western Cape, ZA) Assignees: Kapa Biosystems, Inc. (Wilmington, MA, US)

Abstract

The present invention provides, among other things, chimeric DNA polymerases containing heterologous domains having sequences derived from at least two DNA polymerases that have at least one distinct functional characteristics (e.g., elongation rate, processivity,