Patent
Monomeric peptide multi-agonist targeting the GLP1 receptor and NPY receptors (US Patent 12384825)
Syracuse University · Granted Aug 12, 2025 · Filed Apr 1, 2020
Patent number: 12384825 Kind code: B2 Granted: 2025-08-12 Filed: 2020-04-01 Inventors: Robert P. Doyle (Manlius, NY, US); Brandon Milliken (Syracuse, NY, US) Assignees: Syracuse University (Syracuse, NY, US) CPC: A61K 38/2271
Abstract
A series of chimeric peptides that provide a mechanism for obesity treatment concomitant with T2DM in the form of dual agonism of the anorectic neuropeptide Y-receptor (Y2-R) and the glucoregulatory receptor GLP1-R. Preliminary results show that, dependent