Patent

Dye tagged reagent

Block Engineering, Inc.

US 4,166,105GrantedGranted Aug 28, 1979Filed Dec 20, 1974

Reagents for the detection of specific reactants, such as antigens in biological fluids, comprising a polymer coupled to an antibody, the polymer having a plurality of dye molecules coupled thereto. The reagent is prepared by covalently linking an end functional group of polymers such as polyethylene amine to an antibody, typically through an aldehyde linkage, the polymer molecule having had a plurality of dye molecules, coupled to the polymer through side reactive sites.

Claims
24
3 independent claims
Filing to grant
4.7 years
Pendency

1ClaimsFirst of 24

  1. 1

    A reagent reactive with an analyte body, said reagent comprising; a solution containing a plurality of individual molecules of a first reactant, each of said molecules being a chain molecule having a plurality of reactive sites, substantially only one of said sites being specifically reactable with said analyte body in a reaction wherein several of said molecules can become coupled to said analyte body; like plurality of polyfunctional polymeric backbone molecules substantially each of which is…

2Description

Introduction

This application is a continuation-in-part of copending application Ser. No. 383,892, filed July 30, 1973 now abandoned.

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