Patent

Electrochemical device for detection of selected quorum sensing signals

Danmarks Tekniske Universitet

US 11,169,140 B2GrantedGranted Nov 9, 2021Filed Apr 11, 2017

An electrochemical device for diagnostic purposes, and particularly point-of-care diagnostic purposes, is capable of detecting quorum sensing molecules, such as AHL, within a biological sample with high precision. The device includes at least one reference electrode (RE), at least one counter electrode (CE), and two or more working electrodes (WEs). Each working electrode differs from the other working electrode(s) with respect to at least one of the following characteristics: surface area, size, material, and coating. The device also has a sample receiving area for receiving a biological sample, wherein the electrodes and the sample receiving area is fluidly connected, and a means for transferring the sample to the electrodes for measurement, and a means for displaying a result of the measurement.

Claims
21
3 independent claims
Filing to grant
4.6 years
Pendency
CPC classes
7
B01L · G01N

1ClaimsFirst of 21

  1. 1

    An electrochemical device, comprising: at least one reference electrode (RE); at least one counter electrode (CE); two or more working electrodes (WEs) for detecting a predetermined molecule; wherein each working electrode differs from the other working electrode(s) with respect to at least one of the following characteristics: surface area, size, material, and coating; a sample receiving area for receiving a biological sample, wherein the working electrodes and the sample receiving area are…

2Description

Field of Invention

The present invention relates to an electrochemical device for detecting a presence and measuring a level of a quorum sensing molecule such as N-Acryl homoserine lactones (AHL) in a biological sample. The invention further relates to a method for detecting the presence of a selected quorum sensing molecule in a biological sample, and further to a method for measuring a level of a selected quorum…

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