Application of Franz Bergel and John Albert Stock

WORLEY, Chief Judge.

This is an appeal from the decision of the Board of Appeals of the United States Patent Office affirming the rejection by the Primary Examiner of claims 1 to 6, inclusive, of appellants’ application, No. 415,964, for a patent on chemotherapeutic agents and processes for manufacturing them. Claims 1 and 3, which are typical of the appealed claims, are as follows:

“1. p-Bis- (2-chloroethyl) -amino-phenylalanine.

“3. A process for the manufacture of p-bis-( 2-chloroethyl)-amino-phenylalanine which comprises heating a compound of the general formula:

in which Ri is selected from…