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HistoSonics, Inc. is a privately held medical equipment manufacturing company founded in 2009 by scientists and engineers from the University of Michigan who pioneered the science of histotripsy. Operating in the medical devices sector, HistoSonics specializes in non-invasive therapeutic technologies with its innovative sonic beam therapy platform designed to mechanically destroy unwanted tissue and tumors. Headquartered in Plymouth, Minnesota, HistoSonics has grown to over 200 employees and is dedicated to bringing histotripsy to mainstream clinical practice.
HistoSonics, Inc. has developed a strategic and expanding office footprint to support its commercial and clinical objectives. At the heart of its operations, the HistoSonics corporate office—serving as the primary headquarters—is located in Plymouth, Minnesota. Complementary to its headquarters address, HistoSonics maintains an R&D center in Ann Arbor, Michigan, and a sales office in Minneapolis, Minnesota. This global office strategy supports research excellence, commercialization efforts, and clinical collaborations across the United States, solidifying its status as a leader in non-invasive medical device innovation.
The main HistoSonics headquarters is located at 16305 36th Avenue North, Suite 300, Plymouth, MN 55446, United States. This HistoSonics headquarters address houses executive leadership, administration, and manufacturing operations for the company. The facility is central to HistoSonics’ mission of delivering state-of-the-art histotripsy treatments, offering proximity to medical technology talent and the Minneapolis bioscience ecosystem.
Serving as HistoSonics’ dedicated R&D Center, the Ann Arbor office focuses on pioneering advancements in histotripsy technology. This location is instrumental for collaborative clinical research, engaging with the foundational University of Michigan community, and developing next-generation treatment approaches.
The Minneapolis office operates as a regional sales and marketing center, tasked with growing the adoption of HistoSonics’ therapies across the U.S. commercial landscape. This hub enables the company to support customer relationships, manage sales operations, and extend its market reach from a major Midwest commerce center.
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